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Postgrad Med J 1999;75:451-2 96 -Van Oudheusden LJ, personal commun 97 -Vermeulen RCW, personal commun 98 -Hoffmann GF, Neuropediatrics 1996;27:115-123 99 -Walter JH

R The catalytic triad is Cys68-His107-Asp122, analogous to cysteine proteases

As an adjunct in the treatment of cardiac arrest and profound hypotension Contraindications: (see also - Drug Interactions) Norepinephrine should not be given to patients who are hypotensive from blood volume deficits except as an emergency measure to maintain coronary and cerebral artery perfusion until blood volume replacement therapy can be completed

Although there are numerous chromatographic methods for the determination of Cys, GSH and Hcy in biological samples based on spectrophotometric, spectrofluorimetric and mass spectrometry detection 18,19,20 , only two are dedicated for N-Hcy-Lys measurement 17,21